PE135000: α-GalNAc-PEG3-Thiol – www.teamrr.in

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PE135000: α-GalNAc-PEG3-Thiol

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Description

PE135000: α-GalNAc-PEG3-ThiolC14H27NO8S 369. 43 An D N acetylgalactosamine (GalNAc) ligand equipped with a free thiol through a hydrophilic PEG3 spacer. The thiol reacts with maleimides to form stable thioether conjugates or with other thiols to form disulfide bonds; it is also compatible with thiol gold chemistry for surface immobilization. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor

(11-Azido-3

4-Carboxybutyl N-acetyllactosamine

/ GlcNAc β(1-4) GlcNAc / Chitobiose

C41H61D3O14 / 783

and is a substrate for sialidases

Fmoc-Thr(α-Gal β(1-3)GalNAc)-OH

such as cysteine residues

β-D-GlcNAc-Et-SH

/ α-D-Gal-Butyl-Carboxylic Acid / α-Gal-Bu-CO2H

H-Ser(Gal(β(1-3)GalNAc)-OH

2-[2-(2-Aminoethoxy)ethoxy]ethyl β-D-lactopyranoside

pseudaminic acid is a valuable probe for studying bacterial glycobiology

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