PE936000: Galα(1-3)lactose-β-PEG3-NHCO-PEG10-Maleimide

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Description

PE936000: Galα(1-3)lactose-β-PEG3-NHCO-PEG10-MaleimideN A N A A Gal1 3lactose ( Gal epitope) ligand equipped with a maleimide through an NHCO PEG10 spacer. The maleimide reacts selectively with free thiols, such as cysteine residues, to form stable thioether conjugates. This compound presents a terminal Gal1 3 linkage corresponding to the Gal epitope (Gal1 3Gal1 4GlcNAc Gal1 3lactose), the target of abundant naturally occurring human anti Gal antibodies and central to xenotransplantation and anti Gal

6 / A β-D-N-acetylgalactosamine (GalNAcβ) ligand equipped with an amine-functionalized linker through a hexyl spacer

C29H44D6O2 / 436

The peptide sequence VGVTETP corresponds to positions 103-109 of the mature IFNα2b protein with α-GalNAc glycosylation (Tn Antigen) ocurring at Thr105

/ Fmoc-Ser((Ac)7-Mel-β-D)-OH / Fmoc-Ser(β-D-Mel)-OH

to form stable thioether conjugates

25-Hydroxyvitamin D3 (26

C18H32N2O13 / 484

Tumour-associated carbohydrate antigen (TACA)

27 / An α-D-mannose ligand equipped with a terminal carboxylic acid through a short butyl spacer

A0A2A4NBI4

β-D-Lac-Ethyl-Azide

2-[2-(2-Aminoethoxy)ethoxy]ethyl β-D-lactopyranoside

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